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Article

The relationship between DNA methylation and telomere length in dyskeratosis congenita.

Aging cell - 1 Feb 2012

Gadalla Shahinaz M, Katki Hormuzd A, Shebl Fatma M, Giri Neelam, Alter Blanche P, Savage Sharon A

Abstract excerpt

The regulation of telomere length (TL) is a complex process, requiring the telomerase enzyme complex and numerous regulatory proteins. Epigenetic regulation may also be important in telomere maintenance. Specifically, methylation at subtelomeres is associated with changes in TL in vitro and in mouse models. Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized by exceedingly short...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21981348
DOI: 10.1111/j.1474-9726.2011.00755.x
PMCID: PMC3257380

Genes

DKC1
TERT
TINF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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