Article
Big defensins, a diverse family of antimicrobial peptides that follows different patterns of expression in hemocytes of the oyster Crassostrea gigas.
PloS one - 1 Jan 2011
Rosa Rafael D, Santini Adrien, Fievet Julie, Bulet Philippe, Destoumieux-Garzón Delphine, Bachère Evelyne
Abstract excerpt
BACKGROUND: Big defensin is an antimicrobial peptide composed of a highly hydrophobic N-terminal region and a cationic C-terminal region containing six cysteine residues involved in three internal disulfide bridges. While big defensin sequences have been reported in various mollusk species, few studies have been devoted to their sequence diversity, gene organization and their expression in response to microbial...
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