Article
The thalassemia syndromes: molecular basis and prenatal diagnosis in 1990.
Seminars in hematology - 1 Jul 1990
Kazazian H H
Abstract excerpt
In this review I have outlined the molecular basis and prenatal diagnosis of alpha-thalassemia and then concentrated on the state of our knowledge of the molecular basis of beta-thalassemia and its prenatal diagnosis. I discussed the improved but more complicated genetic counselling now available...
Topics
- Chromosome Deletion
- Genetic Counseling
- Haplotypes
- Humans
- Mutation
- Polymerase Chain Reaction
- Prenatal Diagnosis
- RNA Processing, Post-Transcriptional
- Thalassemia
- Transcription, Genetic