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Article

The binding site of bisphenol A to protein disulphide isomerase.

Journal of biochemistry - 1 Jan 2012

Hashimoto Shoko, Shiomoto Keiko, Okada Kazushi, Imaoka Susumu

Abstract excerpt

Protein disulphide isomerase (PDI) has been isolated as a binding protein of bisphenol A (BPA) in the rat brain. In this study, we determined binding sites of BPA to PDI and characterized the binding site. First, we identified the BPA-binding domain with ab, b'a'c, a, b, b' and a'c fragment peptides of PDI by surface plasmon resonance spectroscopy. BPA interacted with ab, b'a 'c, a and b', suggesting that a and...

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PMID: 21976707
DOI: 10.1093/jb/mvr122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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