Article
Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Dec 2011
Oetting William S, Schladt David P, Leduc Robert E, Jacobson Pamala A, Guan Weihua, Matas Arthur J, Israni Ajay
Abstract excerpt
There have been numerous reports proposing a statistically significant association between a genetic variant, usually in the form of a single nucleotide polymorphism (SNP), and acute rejection (AR). Unfortunately, there are additional publications reporting a lack of association with AR when a different cohort of recipients was analyzed for the same SNP. The objective of this report was to attempt replication of...
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