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Article

Mitochondrial tRNA mutations and disease.

Wiley interdisciplinary reviews. RNA - 1 Jan 2000

Yarham John W, Elson Joanna L, Blakely Emma L, McFarland Robert, Taylor Robert W

Abstract excerpt

Mitochondrial (mt-) tRNA (MTT) gene mutations are an important cause of human morbidity and are associated with a wide range of pathology, from isolated organ-specific diseases such as myopathy or hearing loss, through to multisystem disorders with encephalopathy, gastrointestinal dysmotility, and life-threatening cardiomyopathy. Our understanding of how MTT mutations cause disease remains poor and progress has...

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Identifiers

PMID: 21935892
DOI: 10.1002/wrna.27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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