Article
Fibromyalgia in fragile X mental retardation 1 gene premutation carriers.
Rheumatology (Oxford, England) - 1 Dec 2011
Leehey Maureen A, Legg Wendi, Tassone Flora, Hagerman Randi
Abstract excerpt
OBJECTIVE: FM is a disorder of altered pain regulation and is characterized by pain, fatigue, poor sleep and psychological impairments; thus, it is classified as a central sensitivity syndrome. Female carriers of a premutation in the fragile X mental retardation 1 (FMR1) gene frequently have widespread musculoskeletal pain and sometimes have been diagnosed with FM, especially if they have the motor signs of...
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