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Article

The Core/E1 domain of hepatitis C virus genotype 4a in Egypt does not contain viral mutations or strains specific for hepatocellular carcinoma.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2011

Zhang Xiaoan, Ryu Soo Hyung, Xu Yanjuan, Elbaz Tamerl, Zekri Abdel-Rahman N, Abdelaziz Ashraf Omar, Abdel-Hamid Mohamed, Thiers Valerie, Elena Santiago F, Fan Xiaofeng, Di Bisceglie Adrian M

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) infection is a well-documented etiological factor for hepatocellular carcinoma (HCC). As HCV shows remarkable genetic diversity, an interesting and important issue is whether such a high viral genetic diversity plays a role in the incidence of HCC. Prior data on this subject are conflicting. OBJECTIVES: Potential association between HCV genetic mutations or strain variability...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21925935
DOI: 10.1016/j.jcv.2011.08.022
PMCID: PMC3217131

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