Article
Creutzfeldt-Jakob disease and kuru patients lack a mutation consistently found in the Gerstmann-Sträussler-Scheinker syndrome.
Experimental neurology - 1 Jun 1990
Goldfarb L G, Brown P, Goldgaber D, Asher D M, Rubenstein R, Brown W T, Piccardo P, Kascsak R J, Boellaard J W, Gajdusek D C
Abstract excerpt
We and others have recently reported that patients with the Gerstmann-Sträussler-Scheinker syndrome have a mutation at codon 102 of the gene coding for amyloid protein that accumulates in this disease. We report here that this mutation was not found in 5 familial and 27 sporadic cases of Creutzfe...
Topics
- Base Sequence
- Creutzfeldt-Jakob Syndrome
- Humans
- Kuru
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Slow Virus Diseases