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Cancer‐testis antigen expression and its epigenetic modulation in acute myeloid leukemia

19 Jul 2011

Abstract excerpt

Cancer-testis antigens (CTA) represent attractive targets for tumor immunotherapy. However, a broad picture of CTA expression in acute myeloid leukemia (AML) is missing. CTA expression was analyzed in normal bone marrow (BM) as well as in AML cell lines before and after treatment with demethylating agents and/or histone acetylase inhibitors. Presence of selected CTA with a strictly tumor-restricted expression was...

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PMID: 21898529
DOI: 10.1002/ajh.22141

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