Article
Influence of menopause on adipose tissue clock gene genotype and its relationship with metabolic syndrome in morbidly obese women.
Age (Dordrecht, Netherlands) - 1 Dec 2012
Hernandez-Morante Juan José, Gomez-Santos Cecilia, Margareto Javier, Formiguera Xavier, Martínez Carlos Manuel, González Raquel, Martínez-Augustín Olga, Madrid Juan Antonio, Ordovas Jose María, Garaulet Marta
Abstract excerpt
Menopausal women exhibit a loss of circadian coordination, a process that runs parallel with a redistribution of adipose tissue. However, the specific genetic mechanisms underlying these alterations have not been studied. Thus, the aim of the present study was to determine whether the development of menopause induces an alteration of the genes that control biological rhythms in human subcutaneous (SAT) and...
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