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Article

First isolation of hepatitis E virus genotype 4 in Europe through swine surveillance in the Netherlands and Belgium.

PloS one - 1 Jan 2011

Hakze-van der Honing Renate W, van Coillie Els, Antonis Adriaan F G, van der Poel Wim H M

Abstract excerpt

Hepatitis E virus (HEV) genotypes 3 and 4 are a cause of human hepatitis and swine are considered the main reservoir. To study the HEV prevalence and characterize circulating HEV strains, fecal samples from swine in the Netherlands and Belgium were tested by RT-PCR. HEV prevalence in swine was 7-15%. The Dutch strains were characterized as genotype 3, subgroups 3a, 3c and 3f, closely related to sequences found in...

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PMID: 21829641
DOI: 10.1371/journal.pone.0022673
PMCID: PMC3148228

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