Article
Identification of a DNA methylation point in the promoter region of the bovine CYP21 gene.
Genetics and molecular research : GMR - 1 Jan 2011
da Silva A M, de Freitas M A R, Rios A F L, Renzi A, Lôbo R B, Galerani M A V, Vila R A, Ramos E S
Abstract excerpt
The CYP21 (steroid 21-hydroxylase) gene is involved in the synthesis of steroid hormones. Bov-A2 is a retroposon that is common in ruminant genomes. The promoter region of bovine CYP21 contains a short interspersed nucleotide element of Bov-A2, which overlaps a putative Sp1 binding site. We looked for RFLP/HpaII polymorphism in the Bov-A2 element in bovine Zebu breeds by PCR-RFLP, and examined whether...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.