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Article

Craniofacial divergence and ongoing adaptation via the hedgehog pathway.

Proceedings of the National Academy of Sciences of the United States of America - 9 Aug 2011

Roberts Reade B, Hu Yinan, Albertson R Craig, Kocher Thomas D

Abstract excerpt

Adaptive variation in craniofacial structure contributes to resource specialization and speciation, but the genetic loci that underlie craniofacial adaptation remain unknown. Here we show that alleles of the hedgehog pathway receptor Patched1 (Ptch1) gene are responsible for adaptive variation in the shape of the lower jaw both within and among genera of Lake Malawi cichlid fish. The evolutionarily derived allele...

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Identifiers

PMID: 21788496
DOI: 10.1073/pnas.1018456108
PMCID: PMC3156204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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