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Article

In silico prediction of splice-affecting nucleotide variants.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Houdayer Claude

Abstract excerpt

It appears that all types of genomic nucleotide variations can be deleterious by affecting normal pre-mRNA splicing via disruption/creation of splice site consensus sequences. As it is neither pertinent nor realistic to perform functional testing for all of these variants, it is important to identify those that could lead to a splice defect in order to restrict experimental transcript analyses to the most...

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PMID: 21780003
DOI: 10.1007/978-1-61779-176-5_17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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