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Article

Functional and bioinformatic characterisation of sequence variants of Fad3 gene from flax.

Journal of the science of food and agriculture - 1 Nov 2011

Khadake Rupali, Khonde Vijaykumar, Mhaske Vaishali, Ranjekar Prabhakar, Harsulkar Abhay

Abstract excerpt

BACKGROUND: Desaturases are enzymes that drive the multi-step fatty acid biosynthetic pathway. As evident from directed mutagenesis, single base changes in their polypeptide can potentially alter their structure and may result in altered substrate specificity, regioselectivity and even loss of function. The authors have previously isolated several sequence variants of Δ15 desaturase from flax while attempting to...

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PMID: 21769878
DOI: 10.1002/jsfa.4515

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