Article
Total body irradiation and melphalan as a conditioning regimen for children with hematological malignancies undergoing transplantation with stem cells from HLA-identical related donors.
Pediatric transplantation - 1 Sept 2011
Watanabe Nobuhiro, Takahashi Yoshiyuki, Matsumoto Kimikazu, Horikoshi Yasuo, Hama Asahito, Muramatsu Hideki, Yoshida Nao, Yagasaki Hiroshi, Kudo Kazuko, Horibe Keizo, Kato Koji, Kojima Seiji
Abstract excerpt
Although some studies have reported that TBI and MEL offer an effective conditioning regimen for autologous SCT in acute leukemia, little has been reported regarding outcomes of allogeneic SCT. We retrospectively evaluated outcomes for 50 pediatric patients who underwent allo-SCT conditioned with intravenous MEL (180-210 mg/m(2) ) and fractionated TBI (12-13.2 Gy) from HLA-identical related donors. Nineteen...
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