The genome and surface proteome of <i>Capnocytophaga canimorsus</i> reveal a key role of glycan foraging systems in host glycoproteins deglycosylation

Abstract excerpt

Capnocytophaga canimorsus are commensal Gram-negative bacteria from dog's mouth that cause rare but dramatic septicaemia in humans. C. canimorsus have the unusual property to feed on cultured mammalian cells, including phagocytes, by harvesting the glycan moiety of cellular glycoproteins. To understand the mechanism behind this unusual property, the genome of strain Cc5 was sequenced and analysed. In addition,...

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