Article
Pathogenesis of malignant lymphomas in intravenous drug-abuser, HIV-infected patients.
Cancer detection and prevention - 1 Jan 1990
Boiocchi M, De Re V, Dolcetti R, Volpe R, Gloghini A, Tavian M, Viel A, Maestro R, Carbone A
Abstract excerpt
To study the pathogenesis of malignant lymphomas (ML) in intravenous drug-abuser HIV-infected patients, we analyzed 19 cases of reactive lymphadenopathy (LAS) and 10 cases of ML. Clonality and differences in characteristics of these lymphoproliferative disorders were investigated by immunohistochemical and Ig and TCR gene rearrangement analyses. Rearrangements at the c-myc locus and presence of HIV and EBV viral...
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