Article
Macrophage migration inhibitory factor gene -173G>C polymorphism and risk of bladder cancer in southeast China: a case-control analysis.
Molecular biology reports - 1 Mar 2012
Yuan Qinbo, Wang Meilin, Wang Miaomiao, Zhang Zhengdong, Zhang Wei
Abstract excerpt
Inflammatory factors may promote carcinogenesis. Macrophage migration inhibitory factor (MIF), which is derived from T-cell, known as a member of the transforming growth factor-β (TGF-β) superfamily, plays an important role in the pro- and anti-inflammatory response to infection and in the etiology of bladder cancer. We hypothesized that MIF-173 locus polymorphism might contribute to genetic susceptibility to...
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