The translational science of Marfan syndrome.

Abstract excerpt

Marfan syndrome has changed over the last few years: new diagnostic criteria have been proposed, new clinical entities recognised and life expectancy increased. The role of fibrillin 1, which was initially thought to be mainly structural, has been shown to also be functional. The altered transforming growth factor β pathway is better understood, the importance of epigenetic factors has been demonstrated and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fibrillin-1
• Share to Fibrillins
• Share to France