Article
[C742T mutation of α1, 3 N-acetyl-D-galactosaminyltransferase gene is responsible for A2 subgroup].
Zhongguo shi yan xue ye xue za zhi - 1 Jun 2011
Hong Xiao-Zhen, Yin Yan-Ling, Xu Xian-Guo, Ma Kai-Rong, Lan Xiao-Fei, Liu Ying, Zhu Fa-Ming, Lü Hang-Jun, Yan Li-Xing
Abstract excerpt
The objective of this study was to analyze the molecular genetic basis for 2 individuals with A2B phenotype of ABO subtype. The ABO group antigens on red blood cells were identified by monoclonal antibodies and the ABO antibodies in serum were detected by the standard A, B, O cells. The exon 5 to exon 7 coding region of ABO gene was amplified by polymerase chain reaction (PCR) and the PCR product was sequenced...
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