Article
Short duration treatment in genotype 1 chronic hepatitis C patients with rapid virologic response to pegylated interferon plus ribavirin.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jul 2011
Bonardi Renato, Tabone Marco, Manca Aldo, Pellicano Rinaldo, Ciancio Alessia, Rizzetto Mario
Abstract excerpt
BACKGROUND: In patients with chronic hepatitis C, rapid HCV-RNA clearance under treatment might allow shorter treatment duration without modifying the sustained virological response (SVR) rate. This study evaluated the impact of rapid virological response (RVR) in HCV genotype 1b infection management. METHODS: In an open-label trial, 180 patients received standard doses of peginterferon alfa-2a plus ribavirin....
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