Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

Abstract excerpt

RATIONALE: Defining the biogeography of bacterial populations in human body habitats is a high priority for understanding microbial-host relationships in health and disease. The healthy lung was traditionally considered sterile, but this notion has been challenged by emerging molecular approaches that enable comprehensive examination of microbial communities. However, studies of the lung are challenging due to...

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