Article
Resistance of Helicobacter pylori to quinolones and clarithromycin assessed by genetic testing in Japan.
Journal of gastroenterology and hepatology - 1 Sept 2011
Yamade Mihoko, Sugimoto Mitsushige, Uotani Takahiro, Nishino Masafumi, Kodaira Chise, Furuta Takahisa
Abstract excerpt
BACKGROUND AND AIM: As bacterial resistance to clarithromycin limits the efficacy of clarithromycin-based regimens for Helicobacter pylori infection, attention has turned to quinolone-based rescue therapies. Resistance of H. pylori to both clarithromycin and quinolone can be predicted by genetic testing. Here, we used this approach to evaluate the prevalence of clarithromycin- and quinolone-resistant strains of...
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