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Phylogenomic analyses of malaria parasites and evolution of their exported proteins

15 Jun 2011

Abstract excerpt

BACKGROUND: Plasmodium falciparum is the most malignant agent of human malaria. It belongs to the taxon Laverania, which includes other ape-infecting Plasmodium species. The origin of the Laverania is still debated. P. falciparum exports pathogenicity-related proteins into the host cell using the Plasmodium export element (PEXEL). Predictions based on the presence of a PEXEL motif suggest that more than 300...

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PMID: 21676252
DOI: 10.1186/1471-2148-11-167

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