Article
Mutations in CYP24A1 and idiopathic infantile hypercalcemia.
The New England journal of medicine - 4 Aug 2011
Schlingmann Karl P, Kaufmann Martin, Weber Stefanie, Irwin Andrew, Goos Caroline, John Ulrike, Misselwitz Joachim, Klaus Günter, Kuwertz-Bröking Eberhard, Fehrenbach Henry, Wingen Anne M, Güran Tülay, Hoenderop Joost G, Bindels René J, Prosser David E, Jones Glenville, Konrad Martin
Abstract excerpt
BACKGROUND: Vitamin D supplementation for the prevention of rickets is one of the oldest and most effective prophylactic measures in medicine, having virtually eradicated rickets in North America. Given the potentially toxic effects of vitamin D, the recommendations for the optimal dose are still debated, in part owing to the increased incidence of idiopathic infantile hypercalcemia in Britain in the 1950s during...
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