Article
Cytotype control of Drosophila P element transposition: the 66 kd protein is a repressor of transposase activity.
Cell - 27 Jul 1990
Misra S, Rio D C
Abstract excerpt
Drosophila P transposable elements encode two proteins, an 87 kd transposase protein and a 66 kd protein that has been hypothesized to repress transposition. We have made germline transformants carrying modified P element derivatives that encode only the 66 kd protein and shown that these elements repress transposase activity in both the germline and the soma. The position of these elements in the genome...
Topics
- Animals
- Blotting, Western
- Cloning, Molecular
- DNA Transposable Elements
- Drosophila melanogaster
- Gene Expression Regulation, Enzymologic
- Genotype
- Germ Cells
- Nucleotidyltransferases
- Oogenesis
- RNA, Messenger