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Article

Anaplastic lymphoma kinase translocation: a predictive biomarker of pemetrexed in patients with non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2011

Lee Jeong-Ok, Kim Tae Min, Lee Se-Hoon, Kim Dong-Wan, Kim Soyeon, Jeon Yoon-Kyung, Chung Doo Hyun, Kim Woo-Ho, Kim Young Tae, Yang Seok-Chul, Kim Young Whan, Heo Dae Seog, Bang Yung-Jue

Abstract excerpt

INTRODUCTION: This study compared the efficacy of pemetrexed in patients with anaplastic lymphoma kinase (ALK)-positive versus ALK-negative (epidermal growth factor receptor [EGFR] mutant or wild type [WT] for both ALK and EGFR) non-small cell lung cancer (NSCLC). METHODS: Patients with advanced NSCLC who received second-line pemetrexed and beyond between March 2007 and April 2010 were screened for EGFR mutations...

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Source

Identifiers

PMID: 21642865
DOI: 10.1097/JTO.0b013e3182208fc2

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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