Article
Clinical significance of miR-146a in gastric cancer cases.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2011
Kogo Ryunosuke, Mimori Koshi, Tanaka Fumiaki, Komune Shizuo, Mori Masaki
Abstract excerpt
PURPOSE: The profiles of microRNAs change significantly in gastric cancer. MiR-146a is reported to be a tumor suppressor in pancreatic cancer, breast cancer, and prostate cancer. We investigated the clinical significance of miR-146a in gastric cancer, in particular focusing on hypothetical miR-146a target genes, such as epidermal growth factor receptor (EGFR) and interleukin-1 receptor-associated kinase (IRAK1)....
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