Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rebooting the human mitochondrial phylogeny: an automated and scalable methodology with expert knowledge.

BMC bioinformatics - 19 May 2011

Blanco Roberto, Mayordomo Elvira, Montoya Julio, Ruiz-Pesini Eduardo

Abstract excerpt

BACKGROUND: Mitochondrial DNA is an ideal source of information to conduct evolutionary and phylogenetic studies due to its extraordinary properties and abundance. Many insights can be gained from these, including but not limited to screening genetic variation to identify potentially deleterious mutations. However, such advances require efficient solutions to very difficult computational problems, a need that is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to DNA, Mitochondrial
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria

Share to Phylogeny

Share to Sequence Alignment

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 21595926
DOI: 10.1186/1471-2105-12-174
PMCID: PMC3123235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rebooting the human mitochondrial phylogeny: an automated and scalable methodology with expert knowledge.PMID 21595926Read ↗

Quantifying constraint in the human mitochondrial genome.Semantic proximity Read ↗

Quantifying constraint in the human mitochondrial genomeSemantic proximity Read ↗

A novel phylogenetic analysis and machine learning predict pathogenicity of human mtDNA variantsSemantic proximity Read ↗

Pathogenic mitochondrial genome variation, heteroplasmy thresholding and mitochondrial constraint measures in a healthy older cohortSemantic proximity Read ↗

Automated sequencing of mitochondrial DNA.Semantic proximity Read ↗

MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences.Semantic proximity Read ↗

Mitotree: The Universal Human Mitochondrial Reference Phylogeny at 10× the ResolutionSemantic proximity Read ↗

MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences.Semantic proximity Read ↗

Learning from massive testing of mitochondrial disorders: UPD explaining unorthodox transmission.Semantic proximity Read ↗

The Genographic Project public participation mitochondrial DNA database.Semantic proximity Read ↗

An enhanced MITOMAP with a global mtDNA mutational phylogeny.Semantic proximity Read ↗

SG-ADVISER mtDNA: a web server for mitochondrial DNA annotation with data from 200 samples of a healthy aging cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.