Article
Candidate genes for idiopathic epilepsy in four dog breeds.
BMC genetics - 25 Apr 2011
Ekenstedt Kari J, Patterson Edward E, Minor Katie M, Mickelson James R
Abstract excerpt
BACKGROUND: Idiopathic epilepsy (IE) is a naturally occurring and significant seizure disorder affecting all dog breeds. Because dog breeds are genetically isolated populations, it is possible that IE is attributable to common founders and is genetically homogenous within breeds. In humans, a number of mutations, the majority of which are genes encoding ion channels, neurotransmitters, or their regulatory...
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