Idiopathic Pulmonary Fibrosis — A Sticky Business

Abstract excerpt

Pulmonary fibrosis comprises a spectrum of disease phenotypes, including familial and idiopathic forms. Current research suggests that pulmonary fibrosis is a “two-hit” disease: a genetic predisposition to abnormal alveolar epithelial-cell regulation of the cell cycle and apoptosis combined with environmental stressors, including exposure to known fibrogenic materials (e.g., asbestos, silica, and cigarette...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to Neonatal Respiratory Health Research
• Share to Occupational and environmental lung diseases