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Multiallelic synthetic quality control material: lessons learned from the cystic fibrosis external quality assessment scheme.

Genetic testing and molecular biomarkers - 1 Sept 2011

Berwouts Sarah, Christensen Todd M, Brandon Jill, Bejjani Bassem A, Barton David E, Dequeker Elisabeth

Abstract excerpt

AIM: With the arrival of increasingly complex molecular tests, we are obliged to create new ways to monitor and troubleshoot the underperformance of these multiplex assays. A synthetic multiallelic quality control material has been designed to augment genomic DNA controls. We aimed to evaluate the control on a large scale, testing it on a wide variety of oligonucleotide ligation assays, test protocols, and...

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PMID: 21476898
DOI: 10.1089/gtmb.2011.0015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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