Article
SLC25A13 gene mutations in Taiwanese patients with non-viral hepatocellular carcinoma.
Molecular genetics and metabolism - 1 Jul 2011
Chang Kuei-Wen, Chen Huey-Ling, Chien Yin-Hsiu, Chen Tse-Ching, Yeh Chau-Ting
Abstract excerpt
Mutations of the SLC25A13 gene, which encodes citrin, result in adult-onset type II citrullinemia (CTLN2). Because CTLN2 has been associated with hepatocellular carcinoma (HCC) and may be involved in hepatocarcinogenesis, the objective of this study was to assess the frequency of SLC25A13 mutations in patients with non-viral HCC. A retrospective review of 154 patients with HCC, who underwent total tumor resection...
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