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Article

Molecular cloning and expression of bovine nucleoplasmin 2 (NPM2): a maternal effect gene regulated by miR-181a

29 Mar 2011

Abstract excerpt

BACKGROUND: Nucleoplasmin 2 (NPM2) is an oocyte-specific nuclear protein essential for nuclear and nucleolar organization and early embryonic development. The aims of this study were to clone the bovine NPM2 gene, determine its temporal expression during oocyte development and early embryogenesis, and evaluate the potential role of miRNA-181a in regulation of its expression. METHODS: A 329 bp cDNA fragment was...

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PMID: 21447182
DOI: 10.1186/1477-7827-9-40

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