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Article

Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy.

Ophthalmology - 1 Jul 2011

Nakata Isao, Yamashiro Kenji, Yamada Ryo, Gotoh Norimoto, Nakanishi Hideo, Hayashi Hisako, Tsujikawa Akitaka, Otani Atsushi, Ooto Sotaro, Tamura Hiroshi, Saito Masaaki, Saito Kuniharu, Iida Tomohiro, Oishi Akio, Kurimoto Yasuo, Matsuda Fumihiko, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To investigate whether photodynamic therapy (PDT) outcomes of polypoidal choroidal vasculopathy (PCV) are related to baseline clinical characteristics, smoking history, or genetic factors by analyzing the retreatment-free period after the first PDT. DESIGN: Retrospective cohort study. PARTICIPANTS: The study consisted of 167 patients with PCV who underwent PDT as their first treatment. METHODS: We...

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Identifiers

PMID: 21439646
DOI: 10.1016/j.ophtha.2010.12.011

Genes

SERPINF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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