Article
Exposure to multiple subgenotypes of hepatitis A virus during an outbreak using matched serum and saliva specimens.
Journal of medical virology - 1 May 2011
Amado Luciane Almeida, Villar Livia Melo, de Paula Vanessa Salete, Pinto Marcelo Alves, Gaspar Ana Maria Coimbra
Abstract excerpt
Matched serum and saliva samples were collected simultaneously from 124 subjects exposed during a hepatitis A virus (HAV) outbreak at a daycare center in Rio de Janeiro, Brazil. All samples were tested for IgM and total anti-HAV antibodies by enzyme immunoassay (EIA). HAV was detected by nested PCR in serum, saliva, and water samples employing primers for the VP1/2A region of the viral RNA; all positive products...
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