Article
The domain organization of the bacterial intermediate filament-like protein crescentin is important for assembly and function.
Cytoskeleton (Hoboken, N.J.) - 1 Apr 2011
Cabeen Matthew T, Herrmann Harald, Jacobs-Wagner Christine
Abstract excerpt
Crescentin is a bacterial filament-forming protein that exhibits domain organization features found in metazoan intermediate filament (IF) proteins. Structure-function studies of eukaryotic IFs have been hindered by a lack of simple genetic systems and easily quantifiable phenotypes. Here we exploit the characteristic localization of the crescentin structure along the inner curvature of Caulobacter crescentus...
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