Article
Genetic polymorphism of immunoglobulin G in the mink. VI. A regulatory gene controlling the expression of the gamma-chain constant region allotype of mink immunoglobulin.
Experimental and clinical immunogenetics - 1 Jan 1990
Fomicheva I I, Volkova OYu
Abstract excerpt
We describe here the inheritance of H6, one of the six known allotypes of the gamma-chain constant region of mink immunoglobulin (IgG). H6 is not present in minor concentrations in the serum, and its phenotypic expression is stable. However, in offspring of some of (H6-)X(H6-) crosses. H6 appeared unexpectedly and, by contrast, it disappeared in some H6+/H6+ homozygote offspring. Based on pedigree analysis, a...
Topics
- Animals
- Gene Expression Regulation
- Genes, Immunoglobulin
- Genes, Recessive
- Genes, Regulator
- Immunoglobulin Allotypes
- Immunoglobulin G
- Immunoglobulin gamma-Chains
- Mink
- Pedigree