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Article

Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Yokota Toshifumi, Hoffman Eric, Takeda Shin'ichi

Abstract excerpt

Exon skipping is currently one of the most promising molecular therapies for Duchenne muscular -dystrophy (DMD). We have recently developed multiple exon skipping targeting exons 6 and 8 in -dystrophin mRNA of canine X-linked muscular dystrophy (CXMD), an animal model of DMD, which exhibits severe dystrophic phenotype in skeletal muscles and cardiac muscle. We have induced efficient exon skipping both in vitro...

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Source

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Identifiers

PMID: 21194037
DOI: 10.1007/978-1-61737-982-6_20
PMCID: PMC4491489

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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