Article
Synthesis, oligomerization, and biological activity of the human immunodeficiency virus type 2 envelope glycoprotein expressed by a recombinant vaccinia virus.
Virology - 1 Sept 1990
Chakrabarti S, Mizukami T, Franchini G, Moss B
Abstract excerpt
The full-length envelope gene from an infectious human immunodeficiency virus type 2 (HIV-2) molecular clone was expressed in CD4+ and CD4- cells by a recombinant vaccinia virus vector. Pulse-chase experiments indicated that gp160 was processed into gp120 and gp41 subunits. Although large amounts of gp120 were shed into the medium, the recombinant vaccinia virus-infected cells fused with uninfected CD4+ cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
