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Article

Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla.

Journal of dermatological science - 1 Jan 2011

Inui Shigeki, Itami Satoshi

Abstract excerpt

Androgenetic alopecia (AGA) is characterized by vellus transformation of scalp hairs, corresponding to hair follicle miniaturization during repeated hair cycles with shortened anagen phase. This phenomenon is mediated mainly by androgen. Then, the multi-step molecular pathway of androgen can be involved in the pathogenesis of AGA. The expression of type II 5α-reductase is higher in dermal papilla cells from AGA...

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Source

Identifiers

PMID: 21167691
DOI: 10.1016/j.jdermsci.2010.10.015

Genes

AGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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