Article
[Gene mapping of developmental dysplasia of the hip in chromosome 17q21 region].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2010
Li Lian-yong, Sun Xue-ke, Zhao Qun, Zhang Li-jun, Li Qi-wei, Wang Li-li, Gao Hong
Abstract excerpt
OBJECTIVE: To map the susceptibility gene of developmental dysplasia of the hip(DDH) in chromosome 17q21 region. METHODS: According to the number of alleles (≥ 5), heterozygosity (≥ 0.70) and polymorphic information content (PIC≥ 0.5), 11 STR markers in the 17q21 region were chosen for transmission disequilibrium test (TDT). STR markers were amplified by PCR and genotypes were analyzed by capillary...
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