Article
Hepatoblastoma in a 4-year-old girl with Fanconi anaemia.
Acta paediatrica (Oslo, Norway : 1992) - 1 May 2011
Kopic Sascha, Eirich Katharina, Schuster Beatrice, Hanenberg Helmut, Varon-Mateeva Raymonda, Rittinger Olaf, Schimpl Günther, Schindler Detlev, Jones Neil
Abstract excerpt
CASE REPORT: Hepatoblastoma was diagnosed in a 4-year-old girl receiving growth hormone substitution therapy for short stature. Owing to multiple congenital malformations, VACTERL-H (vertebral, anal, cardiac, tracheal, renal and limb anomalies with hydrocephalus) association had been suggested. Elevated chromosomal breakage rates and G2 phase arrest induced by DNA-crosslinking agents in cellular assays confirmed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.