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Article

Meiotic activity in orthotopic xenografts derived from human postpubertal testicular tissue

30 Nov 2010

Abstract excerpt

BACKGROUND: Grafting of frozen-thawed testicular tissue has been suggested as a novel fertility preservation method for patients undergoing gonadotoxic treatments. However, this technique still needs further optimization before any clinical application. So far, grafting of human testicular tissue has only been performed to the back skin of nude mice and has shown spermatogonial stem-cell survival and occasionally...

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PMID: 21123192
DOI: 10.1093/humrep/deq321

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