Article
HLA-DR6 association confers increased resistance to T. rubrum onychomycosis in Mexican Mestizos.
International journal of dermatology - 1 Dec 2010
Asz-Sigall Daniel, López-García Lirio, Vega-Memije María Elisa, Lacy-Niebla Rosa María, García-Corona Cristina, Ramírez-Rentería Claudia, Granados Julio, Villa Antonio, Ameen Mahreen, Arenas Roberto
Abstract excerpt
BACKGROUND: Onychomycosis is multifactorial in origin. Studies have suggested an autosomal dominant pattern of inheritance and human leukocyte antigen DR4 (HLA-DR4) has been shown to protect against onychomycosis in an Ashkenazi Jewish population. AIM: This study investigates HLA class II association in a Mexican Mestizo population with Trichophyton rubrum onychomycosis. METHODS: This was a prospective...
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