Article
Quantitative control of organ shape by combinatorial gene activity.
PLoS biology - 9 Nov 2010
Cui Min-Long, Copsey Lucy, Green Amelia A, Bangham J Andrew, Coen Enrico
Abstract excerpt
The development of organs with particular shapes, like wings or flowers, depends on regional activity of transcription factors and signalling molecules. However, the mechanisms that link these molecular activities to the morphogenetic events underlying shape are poorly understood. Here we describe a combination of experimental and computational approaches that address this problem, applying them to a group of...
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