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Article

Pathogenicity of exonic indels in fused in sarcoma in amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Feb 2012

Rutherford Nicola J, Finch Nicole A, DeJesus-Hernandez Mariely, Crook Richard J P, Lomen-Hoerth Catherine, Wszolek Zbigniew K, Uitti Ryan J, Graff-Radford Neill R, Rademakers Rosa

Abstract excerpt

Insertion and deletion variants (indels) within poly glycine tracts of fused in sarcoma (FUS) were initially reported as causative of disease in amyotrophic lateral sclerosis (ALS). Subsequent studies identified similar indels in controls and suggested that these indels may confer susceptibility to ALS. We aimed to elucidate the role of previously published and novel exonic indels in FUS in an extensive cohort of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21074900
DOI: 10.1016/j.neurobiolaging.2010.09.029
PMCID: PMC3130814

Genes

FUS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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