Article
Towards the integration of genetic knowledge into clinical practice.
Nephron. Clinical practice - 1 Jan 2011
Ong Albert C M, Devuyst Olivier
Abstract excerpt
The past three decades have seen a revolution in molecular biology and genetics that have changed the way we define disease, diagnose it, understand pathogenesis, initiate new treatments and assess individual responsiveness to intervention. The 'new genetics' has made its biggest impact on monogenic or 'rare' diseases, although its impact is increasingly being felt in the polymorphic so-called 'common' diseases....
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